Powder Grinding Machines

Why LTPM Powder Grinders for Pharmaceutical Applications?

Achieving a controlled, narrow particle size distribution (PSD) is crucial for:

• Content Uniformity: Ensures homogeneous distribution of API in powder blends for capsules and tablet granulations.

• Controlled Dissolution: Fine-tuning particle size directly impacts drug release profiles.

• Process Efficiency: Consistent powder flowability improves the performance of downstream equipment like our capsule fillers and tablet presses.

• Stability & Efficacy: Gentle, low-temperature milling options preserve the potency of heat-sensitive and volatile compounds.

LTPM grinders are designed with these pharmaceutical imperatives in mind, bridging the gap between raw material preparation and final dosage form manufacturing. Contact our pharmaceutical milling experts to discuss your specific material and PSD requirements.

Key Design Features for GMP & Pharmaceutical Compliance

• Hygienic & Cleanable Design: Primary contact parts constructed from 316L stainless steel. Smoothed surfaces, minimal dead corners, and quick-disassembly clamps facilitate full cleaning and inspection.

• Containment & Dust Control: Options for integrated dust collectors, cyclone separators, and sealed systems to protect operators, prevent cross-contamination, and handle potent compounds.

• Material Integrity Protection: Designs focused on low heat generation (Hammer Mills with cooling jackets, Jet Mills) and low iron contamination (ceramic or specialized alloy options available) to protect sensitive APIs.

• Documentation & Validation Support: Equipment supplied with necessary documentation to support your IQ/OQ protocols. Design complies with cGMP principles for solid oral dosage form manufacturing.

How to Select the Right Mill for Your Pharmaceutical Process?

Choosing the correct mill depends on several factors:

• Material Properties: Is it heat-sensitive? Brittle or fibrous? What is the initial and desired final particle size?

• Process Stage: Is this for primary crushing, granule sizing, or final API micronization?

• Batch vs. Continuous: What is your required capacity (from lab-scale R&D with LTQM-20 to full production)?

• Containment Level: Does the process require open, contained, or fully isolated handling?

Our technical team can help you analyze your requirements and recommend the optimal milling solution to integrate seamlessly with your LTPM tablet press or capsule filling line.